Volume 26 Issue 4 - April 11, 2014 PDF
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Commentary

Research Express@NCKU Apr. 11 ~ Apr. 24, 2014

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Human CD133 gene transduction enhances the tumorigenicity of glioma cells
Shun-Fen Tzeng

Gliomas are classified into grade I–IV by the World Health Organization (WHO) on the basis of histological and clinic features. Glioblastoma multiforme (GBM) is the most common and aggressive form of malignant astrocytoma. CD133 (Prominin-1/AC133) is generally used as a cell surface marker found on multipotent stem cells and tumor stem-like cells. Yet, its function remains unclear. We generated a genetically modified rat …

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