The membrane glycoprotein thrombomodulin (TM) has been implicated in keratinocyte differentiation and wound healing, but its specific function remains undetermined. In this study, epidermis-specific TM knockout mice (TM^lox/lox;K5-Cre) were successfully generated to investigate the function of TM in these biological processes.

Histochemistry analysis of the mouse tail cross …

The quinoxaline 1,4-di-N-oxide derivatives with antimicrobial activity (carbadox and olaquindox in this study) are food additives for animal feeds to prevent epidemics and increase the growth rate and weight gain. ^[1] Owing to their quindoxin moiety, they are suspected of inducing strand scission in DNA and have long been recognized as genotoxic. ^[2-3] As carbadox enters the …

Sequence variation plays a critical role in how genes and gene products connect to human health or disease. In recent years, several text mining studies have attempted to develop and use sequence variation recognition tools to process the biomedical literature and have obtained reasonably successful results. However, most of these tools only handle formal variation mentions of a specific type of …

The formation of nanoporous palladium-silver (NPPS) structure through galvanic replacement reaction (GRR) of nanoporous silver (NPS) and palladium (II) nitrate is monitored by chronopotentiometry. During the GRR, the potential of the NPS varied with time from the formal potential of the Ag(I)/Ag couple toward that of the Pd(II)/Pd couple and approaches a “steady-state” value. The potential …