Volume 8 Issue 9 - May 15, 2009
Articles Digest

Research Express@NCKU May 15 ~ May 21, 2009

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Interval Estimation of Binomial Proportion in Clinical Trials with a Two-Stage Design
Yunchan Chi

1.Introduction

In a drug development process, the primary goal of Phase II clinical trials is to determine whether there is sufficient evidence of efficacy and safety to make it worth further study in a Phase III clinical trial. For example, suppose a new drug is developed for patients with liver cancer. To investigate whether this new drug ...


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Blending of poly(3,4-ethylenedioxythiophene) poly(styrenesulfonate) with poly(ethyleneimine) as an active layer in depletion-mode organic thin film transistors
Yeong-Her Wang

With their high potential in terms of flexibility, easy process,  and low cost, organic semiconductor have been developed for thin film transistor (TFT) applications. Doped poly(3,4-ethylenedioxythiophene) (PEDOT) displays conductivities ranging from 1-100 S/cm depending on the counter ions. With poly(styrene sulfonic acid) (PSS) as the counter ion, the conductivity is typically 10 S/cm ...

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Abrasion Damage of Geogrids Induced by Turbid Flow
Ching-Chuan Huang

ABSTRACT
A circular flow chamber is developed to study the abrasion damage of three woven geogrids.  This chamber creates consistent turbid flow conditions in terms of flow velocities and particle concentrations, and is an effective tool for laboratory studies on abrasion damage of geosynthetic materials induced by turbid flows.  Two types of damages ...


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The functional insufficiency of human CD4+CD25high T regulatory cells in allergic asthma is subjected to TNF-α modulation
Jiu-Yao Wang

Allergic asthma is characterized by a systemic, exacerbate Th2 cytokine immune response to environmental allergens that leads to airflow obstruction, airway hyper-responsiveness (AHR), and ongoing active airway inflammation (1). Despite recent progress in the understanding of the role of Th2 and inflammatory cytokines, such as TNF-α(2), in the pathogenesis of the disease, ...

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Interactions between Poly(N-vinylformamide) and Sodium Dodecyl Sulfate As Studied by Fluorescence and Two-Dimensional NOE NMR Spectroscopy
Sheng-Shu Hou

The interactions between water-soluble polymers and surfactants have been extensively studied for more than four decades. The mixed polymer/surfactant systems are of interest not only because of many prevalent and hopeful applications such as pharmaceutical formulation, food products, detergency, paints and inks, improved oil recovery, etc., but also because of the nature of interaction between ...

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